Correction: The growing applications of click chemistry
نویسندگان
چکیده
منابع مشابه
The growing impact of click chemistry on drug discovery.
Click chemistry is a modular approach that uses only the most practical and reliable chemical transformations. Its applications are increasingly found in all aspects of drug discovery, ranging from lead finding through combinatorial chemistry and target-templated in situ chemistry, to proteomics and DNA research, using bioconjugation reactions. The copper-(I)-catalyzed 1,2,3-triazole formation ...
متن کاملDevelopment and Applications of Click Chemistry
Reported by Gregory C. Patton November 8, 2004 INTRODUCTION Secondary metabolites produced in Nature contain diverse architectures with extensive carboncarbon bond networks. These compounds often possess important biological activities that make them potential therapeutic agents. However, drug discovery based on these natural products is generally slow, costly, and hindered by complex syntheses...
متن کاملThe growing impact of bioorthogonal click chemistry on the development of radiopharmaceuticals.
Click chemistry has become a ubiquitous chemical tool with applications in nearly all areas of modern chemistry, including drug discovery, bioconjugation, and nanoscience. Radiochemistry is no exception, as the canonical Cu(I)-catalyzed azide-alkyne cycloaddition, strain-promoted azide-alkyne cycloaddition, inverse electron demand Diels-Alder reaction, and other types of bioorthogonal click lig...
متن کاملClick chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.
In recent years, there has been an ever-increasing need for rapid reactions that meet the three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions would allow medicinal chemistry to keep pace with the multitude of information derived from modern biological screening techniques. The present review describes one of these reactions, the 1,3-dipolar cycloa...
متن کاملApplications of azide-based bioorthogonal click chemistry in glycobiology.
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments. For glycobiology, bioorthogonal click chemistry has created a new method for glycan non-invasive imaging in living systems, selective metabolic engineering, and offered an elite chemical handle for biological manipulation and glycomics st...
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ژورنال
عنوان ژورنال: Chemical Society Reviews
سال: 2016
ISSN: 0306-0012,1460-4744
DOI: 10.1039/c6cs90108e